Applying Choosing Wisely: Antinuclear Antibody (ANA) and Sub- Serology Testing in a Safety Net Hospital System

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Applying Choosing Wisely: Antinuclear Antibody (ANA) and Sub-Serology Testing in a Safety Net Hospital System.

OBJECTIVE In 2013, the American College of Rheumatology (ACR) participated in the Choosing Wisely campaign and devised a recommendation to avoid testing antinuclear antibody (ANA) subserologies without a positive ANA and clinical suspicion of disease. The goals of our study were to describe ANA and subserology ordering practices and predictors of ordering concurrent ANA and subserologies in a s...

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Low value cardiac testing and Choosing Wisely.

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Antinuclear antibody (ANA)-positive thrombocytopenia: primary, but with a difference.

1. Gandhi MK, Khanna R. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect Dis. 2004;4:725-738. 2. Hislop AD, Taylor GS, Sauce D, Rickinson AB. Cellular responses to viral infection in humans: lessons from Epstein-Barr virus. Annu Rev Immunol. 2007;25: 587-617. 3. Gandhi MK, Wills MR, Okecha G, et al. Late diversification in the clonal composition...

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Antinuclear antibody testing.

The ANA test is an excellent screening test for patients with SLE and a few other connective tissue diseases. The LE cell preparation is an assay that is subjective and costly. Because of the presence of a superior screening test (the ANA) and superior specific auto-antibody tests, the author recommends that the use of LE cell preparations be discontinued. ANA screening tests may be performed e...

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BACKGROUND For the serological diagnosis of systemic autoimmune rheumatic diseases, a two-tier approach starting with sensitive antinuclear antibody (ANA) detection by indirect immunofluorescence (IIF) on HEp-2 cells followed by characterization of positive findings with different immunoassays is recommended. To overcome drawbacks of this approach, we developed a novel technique allowing the co...

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ژورنال

عنوان ژورنال: The Open Rheumatology Journal

سال: 2015

ISSN: 1874-3129

DOI: 10.2174/1874312901409010082